Outcomes of electrically stimulated gracilis neosphincter surgery

Outcomes of electrically stimulated gracilis neosphincter surgery.

OBJECTIVES To examine patient quality of life (QoL) and long-term costs of electrically stimulated gracilis neosphincter surgery (ESGNS). DESIGN Independently conducted prospective case-comparison study of patients at the Royal London Hospital (RLH), plus a cross-sectional study of outcomes of ESGNS performed at three other UK centres. PARTICIPANTS Cases were patients who underwent ESGNS at...

Modelling of the Electrically Stimulated Cochlea

Fluorescence imaging of electrically stimulated cells.

Designing high-throughput screens for voltage-gated ion channels has been a tremendous challenge for the pharmaceutical industry because channel activity is dependent on the transmembrane voltage gradient, a stimulus unlike ligand binding to G-protein-coupled receptors or ligand-gated ion channels. To achieve an acceptable throughput, assays to screen for voltage-gated ion channel modulators th...

The Effect of Voluntary and Electrically Stimulated Quadriceps Muscle Fatigue on Postural Control

Purpose: The present study aimed to investigate the effect of voluntary and electrically stimulated quadriceps muscle fatigue on postural control. Methods: Sixteen healthy young males participated in this quasi-experimental study. All subjects performed two fatiguing exercises with equal intensity of isometric maximal voluntary contraction: Voluntary (VOL) and Electrical Stimulation (ES). The ...

Signal transduction in electrically stimulated bone cells.

BACKGROUND Electrical stimulation is used to treat nonunions and to augment spinal fusions. We studied the biochemical pathways that are activated in signal transduction when various types of electrical stimulation are applied to bone cells. METHODS Cultured MC3T3-E1 bone cells were exposed to capacitive coupling, inductive coupling, or combined electromagnetic fields at appropriate field str...